ea0063p347 | Thyroid 1 | ECE2019
Timon Iciar Martin
, Ruiz Inmaculada Moreno
, Penalver Juan Jose Marin
, Abiega Beatriz Ugalde
, Pita Olalla Meizoso
, Collantes Cristina Sevillano
Introduction: There are a few hypothyroid patients who are refractory to standard thyroid hormone replacement treatment and require unexpectedly high doses of levothyroxine. In addition to clinical situations where hypothyroid patients are non-compliant (pseudomalbsortion), or where there is the possibility of excipient-induced disease exacerbation, therapeutic failure may be due to impaired absorption of the administered drug. The common approach to managing patients is to es...